I don't think these drugs can be compared to other more physical related illness remedies for a few reasons, one in particular related to sila: These drugs are taken with the intention of altering the mind.
As for the effectiveness and harmfulness of these drugs in general, this is not quite as related, but still relevant.
This is a good article on the subject. http://www.scribd.com/doc/19458201/The- ... t-Whitaker
Also askapatient.com is a good source of user reports, there are thousands.
Another reason these drugs are more suspicious than physical ones is that they cause a host of effects that indicate some mental change, maybe more-so than any physical-related remedy.
Lastly, these drugs are introducing a physical change, however there is no observed physical abnormality. Actually, it is observed that at least some of these drugs create physical abnormalities.
I think sila is individual and circumstantial to a certain extent but here I think too many allowances are made.
So, there you go,have a good day..